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Fig. 6. The complete amino acid sequence of human DNA topo II{alpha}accession number NP 001058). The active-site tyrosine residue (805) is indicated (*); NES1017-1028, C1017DILRDFFELRLK1028 and NES1054-1066, C1054FILEKIDGKIIIE1066 are shaded; bipartite NLS is single underlined; Ser/Thr CK2 phosphorylation sites are italicized; the predicted coiled-coil region is boxed.





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