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Fig. 8. The effect of surface discontinuities on cell adhesion on the different feature sizes. Both the average number of discontinuities that a cell interfaced and the number of adherent cells present after exposure to a wall shear stress of 10 Pa for 15 minutes are presented as a functions of surface topography. The number of surface discontinuities that a cell spanned was determined from SEM images of cells on the different topographical areas. For SEM analysis the total number of cells examined was 25. Mean±s.e.m. 4 ≤n≤7.





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