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Fig. 6. Rac1 activation by syndecan-4 clustering. Time course of Rac1, RhoA and Cdc42 activation following antibody oligomerization of FcR-S4 chimeras. GST pull down assays with specific substrates were performed as described in the Materials and Methods. Note activation of Rac1 5 minutes after initiation of syndecan-4 oligomerization while neither RhoA nor Cdc42 activity is changed.





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