spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 8. Specific role of Rho GTPases in syndecan-4 endocytosis. The contributions of Rac1, Cdc42 and RhoA GTPases to syndecan-4 endocytosis were studied in FcR-S4-expressing RFPEC transiently transfected with eGFP-tagged dominant negative and constitutively active constructs. (A) A dominant negative Rac1 completely inhibited (left panels) while a constitutively active Rac1 stimulated (right panels) FcR-S4 endocytosis. (B) The expression of a dominant negative Cdc42 construct (left) somewhat inhibited FcR-S4 endocytosis while a constitutively active (right) Cdc42 constructs had no effect. (C) The expression of dominant negative (left) or constitutively active (right) RhoA constructs had no effect on FcR-S4 endocytosis. CA, constitutively active; DN, dominant negative. Scale bars, 10 µm.





Right arrow Return to article