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Fig. 5. Effects of mAb16-39 on DNA synthesis. Serum-deprived 2-C4, parental NIH 3T3 (A), or SK-N-SH (B) cells were cultured for 2 days in the presence of various concentrations (nM) of normal rat IgG, mAb16-39, NGF, or 5% serum as indicated. () in the serum column indicates 0.1% serum. [3H]thymidine uptake over the last 4 hours of culture was measured and is presented as the mean±s.e.m. of three experiments performed in duplicate.