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Fig. 6. Development of the vascular system in P0-P9 retinas. (A-D) Blood vessels identified by isolectin staining and astrocytes identified by S100 antibodies at the front of the expanding vascular plexus at P7. The network of astrocytes at the vascular front, the progression of retinal vascularization (A,B) and fibronectin production (C,D) were similar in wild-type and GFAP–/– Vim–/– mice. (E,F) The ratio of the radius of the vascular plexus to that of the retina (Lv/Lr; E) was similar in wild-type and GFAP–/– Vim–/– mice at P0-P9 (F). (E inset) The region depicted in (A-D). Scale bars, 100 µm (A-D).





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