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Fig. 4. Mutations in the fission yeast ctf18 and dcc1 homologs cause meiosis II non-disjunction. Schizosaccharomyces pombe wild-type (PY796xJY333) (A), ctf18– (PX101xPX131) (B) and dcc1– (PX100xPX128) (C) strains carrying one homolog of chromosome 1 marked by GFP (heterozygous cen1-GFP) were sporulated and analysed under the fluorescence microscope. cen1-GFP is shown in white and the asci are highlighted using margins. (D) Diagram showing the percentages of cen1-GFP meiosis II non-disjunction in fission yeast wild type, ctf18– and dcc1– tetrads. More than 200 tetrads were scored for each strain.





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