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Fig. 10. Effects of CaD39-AB on cell growth. 4x104 39C15 (filled circles), m5-8 (open circle) and m4-65 (filled triangles) cells were plated on 60-mm dishes. Cells from each plate were trypsinized and counted every 24 hours. Cell numbers were plotted against culturing time. Calculated doubling times for 39C15, m5-8 and m4-65 were 16 hours, 21 hours and 24 hours, respectively. The expression level of mutant CaD39-AB protein was inversely proportional to growth rate.