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First published online July 30, 2004

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Chromatin-remodelling machines

Remodelling of nucleosomes on DNA controls access of regulatory proteins to their target sequences. In this way, it endows chromatin with the plasticity required for regulation of transcription, DNA replication, recombination and repair. A variety of large, ATP-dependent multiprotein complexes carry out such remodelling, and these have been identified in yeast, flies and mammals. In Cell Science at a Glance, Anton Eberharter and Peter Becker survey the known remodelling machines, as well as the different `nucleosomoid' structures that they generate (see p. 3707 + poster).

Related articles in JCS:

ATP-dependent nucleosome remodelling: factors and functions

Anton Eberharter and Peter B. Becker
JCS 2004 117: 3707-3711. [Full Text]  

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in JCS Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content