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Fig. 9. Timeline of the reconfiguration of a multiprotein complex at condensed chromatin. Proteins from different nuclear domains accumulate together at heterochromatin in an apparent ATRX-based complex during late S-phase. Signaling for this change is due to a shift in phosphorylation of the heterochromatin-based ATRX. This complex is resolved during G2 phase, when ATRX recruitment to ND10 is mediated by Daxx.





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