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Fig. 6. p53 increases PDGF ß-receptor promoter activity. (A) 3T3 cells were co-transfected with the HindIII/SacI or the SacI/SacI constructs (wild type or CCAAT-mutant) together with p53 or vector alone. The expression of p53 is shown by immunoblotting. (B) SL2 cells were co-transfected with the SacI/SacI construct and NF-Y, Sp1, NF-Y + Sp1 or vector alone in combination with p53. Luciferase activity was measured as described above.