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Fig. 7. A model for genetic regulation of meiosis and telomere clustering. Regulatory pathways in the normal process of meiosis (A), in meiosis induced by byr1DD expression (B), and in meiosis induced by Pat1 inactivation (C). Activation and inhibition are indicated by arrows and crossing bars, respectively. Direct biochemical interaction has been proved for the inhibition of Pat1 by Mei3, the inhibition of Mei2 by Pat1, and the activation of Spk1 by Byr1 (indicated by a single arrow or bar). Other regulatory pathways indicated by two successive arrows or bars are conceptual, and could be indirect.





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