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Fig. 6. Actinomycin D delayed the nucleolar release of TRF2 in G2 phase and mitosis. The effect of actinomycin D on the nucleolar localization of human TRF2 was examined at G2 phase, as determined by the expression of cyclin B1 (A-C), or at early prophase and compared to the localizations of B23 (D-F) and Ku86 (G-I). Arrows indicate the position of the nucleoli.





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