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Fig. 6. Laminin matrices assembled on artificial lipid films present distinguished morphologies. Laminin matrices were assembled directly onto glass coverslips at the conditions indicated in the figure (A,D,G,H) or onto lipid films previously adsorbed to the coverslips (B,C,E,F). After 12 hours, artificial matrices were fixed and processed for immunostaining with anti-laminin antibodies. Bulky protein aggregates are observed in panels A to C, while lace-like polymers are seen in panels E to G. Panels D and H show conditions at which aggregation does not occur and laminin adsorbs evenly on the coverslips, probably as individual trimers. Bar, 50 µm.





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