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Fig. 5. Role of SNX16 in the regulation of EGF-induced gene transcription. COS-7 cells were transfected with the reporter genes SRE-Luc (10 ng) and lacZ (20 ng) and with FLAG-tagged SNX16^WT and SNX16^Y145A (10 ng). After EGF treatment for the indicated times, EGF-induced increase in luciferase activity was quantified and expressed as mean±s.d.

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