spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Expression of JMD-deleted E-cadherin affects the eyes and cartilage. (A) Embryos were injected at the 8-cell stage in the dorsal-animal region and scored at stage 42 for the eye phenotype (a,c) and stage 46 for the cartilage phenotype after Alcian Blue staining (b,d). Embryos injected with 1 ng mE-cadh{Delta}JMD show malformation of the eye (c,d) compared with control injected embryos (a,b). The arrowhead in (b) indicates a patch of retinal pigmentation in the brain. (B) Graph representing the effect of mE-cadh{Delta}JMD on the size of the craniofacial cartilage. Three normalized experiments are represented in one graph. The width of the head was calculated as in the legend of Fig. 3. The effect of mE-cadh{Delta}JMD can be partially rescued by co-injection of 150 pg wild type (WT) RhoA or 50 pg dominant negative (DN) Rac (values are statistically different from those injected with mE-cadh{Delta}JMD RNA alone).





Right arrow Return to article