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Fig. 2. Electroretinographic responses suggest abnormal synaptic transmission between photoreceptors and retinal interneurons. (A) Implicit times of a-wave (left) and b-wave (right) peaks, with standard errors, plotted as a function of flash intensity. Times are significantly longer in the Myo5a^d-l/Myo5a^d-l (n=10) group compared with the controls [Myo5a^d/Myo5a^{d or d-l} (n=12; no difference was observed between the two control genotypes, P>0.25); a-wave P<0.01 from 3 log units of attenuation; b-wave, 7.2-2.4, P<0.05, 1.8-0 P<0.001]. (B) Ratios of b- to a-wave amplitudes are significantly smaller in dilute lethal mutants than the control dilute group (P $≤$ 0.001 from 2.4 log units of attenuation).

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