spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 9. Long-term inhibition of MAP kinase activity induces net retrograde NF transport. (A-C,E,G) GFP-transfected (A-C,G) and mitotracker-labeled (E) NB2a/d1 cells sequentially captured at the indicated intervals following treatment with PD98059. Selected GFP-tagged structures undergoing retrograde transport are indicated by arrows; not all such structures are indicated. (D) Data derived from over 100 individual GFP-tagged structures from multiple cultures from three experiments. Note that this more prolonged treatment with PD98059 induces a shift from net anterograde to net retrograde transport of GFP-tagged structures. Note that treatment with PD98059 for 3 hours did not reduce the overall level of mitotracker-labeled structures within axonal neurites (E, F). GC in panel C denotes the growth cone (Hillock). Scale bar in C (refers to all panels), 10 µm.





Right arrow Return to article