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Fig. 6. Role of N-cadherin in wound-healing migration of myofibroblasts. (A-B) Confluent monolayers of serum-starved myofibroblasts were wounded with a razor blade. Migration of myofibroblasts was quantified as number of intersections/microscopic field at different distances after a 24-hour treatment with (A) N-cadherin neutralizing mAb or peptide and (B) electroporation in the presence of N-cadherin siRNA. Of the different conditions tested in A, representative pictures were taken. The arrowhead indicates the scratch (time 0) made by the razor blade. Bar, 100 µm.





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