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Fig. 8. Role of N-cadherin in the polarity of myofibroblasts. (A) Representative phase-contrast micrographs of DHD-Fib myofibroblasts, taken 8 hours after wounding. Cells were treated with huN-CAD10scr or huN-CAD10 peptide. Loss of polarity is indicated by loss of unidirectional migration. Bars, 50 µm. (B) (upper panel) Golgi-complex immunostaining of DHD-Fib myofibroblasts in confluent conditions or 8 hours after wounding. Direction of movement is shown by arrows; (lower panel) bars show percentage of cells with their Golgi complex facing the wound for 50 cells of the first 2 front rows or at random in wounded or confluent monolayers. Bar, 25 µm.





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