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Fig. 3. (A) Effect of RA treatments on PCNA expression in parental and nNOS overexpressing SK-N-BE cells. Levels of PCNA were visualized by western blot. (B) Effect of RA treatments on ODC activity in parental and clone-4 cells. Bars are the mean±s.e.m. of three experiments. *, P<0.01 compared with control (Bonferroni's test after ANOVA). (C) Quantification of cell death after 1-7 days RA exposure by a specific ELISA kit. Bars are the mean±s.e.m. of four experiments. *, P<0.01 compared with clone 4 without RA; #, P<0.01 compared with parental cells without RA (Bonferroni's test after ANOVA).





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