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Fig. 3. Roscovitine causes cortical actin rearrangement. Anterior pituitary cells maintained in control medium (-Ros) or treated with 10 µM roscovitine (+Ros) were fixed and visualized simultaneously for F-actin using TRITC-phalloidin (top) and prolactin (center) (A) or F-actin (top) and growth hormone (center) (B). Bottom, merged images; bar, 10 µm.