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Fig. 8. (Macro)pinocytic burst in response to growth factors or phorbol ester. (A) Rat-1/tsLA29 fibroblasts; (B) MDCK/tsLA31 cells. Fluid-phase endocytosis was measured by a 5-minutes uptake of HRP in the presence or absence of the indicated concentrations of PDGF-BB, EGF or PMA added concomitantly. Values represent means±s.d. of three dishes from one representative experiment out of three (***P<0.001, **P<0.01 by Student's t-test).