spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. Interaction of DSB repair proteins. (A,B) Close interaction is found e.g. for Rad51/Rad52 and Mre11/Rad50, where not only optical co-localisation can be found, but also the FRET effect is positive and shows close spatial proximity. (C) For Rad51/Rad52 and Mre11/Rad50, molecular interaction can be seen after UV-A exposure as demonstrated by the inducible complexes seen during Co-IP. (D-J) Optical co-localisation as merged images (arrows point to co-localisation spots) in G2-enriched cultures. These examples show that on some, but not all, DSB sites the DSB proteins from both pathways are present, but they do not have direct molecular interaction. The complete data from these experiments are summarised in Table 1.





Right arrow Return to article