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Fig. 4. Hyoglossus muscle was used as a positive control to determine the influx transfer constant of [¹²⁵I]-RAP during in situ brain perfusion. The value was higher for [¹²⁵I]-RAP when compared with that of [¹²⁵I]melanotransferrin and the paracellular permeability marker [^99mTc]-albumin.

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