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Fig. 1. Caenorhabditis elegans cathepsin L protease mutant cpl-1(ok360) phenotype could be rescued efficiently by extrachromosomal transformation with the wild-type Ce-cpl-1 gene. Western blot of wild-type N2 (lane 1), rescued homozygous cpl-1 mutant (lane 2) and non-rescued homozygous cpl-1 mutant (lane 3) adult worm extracts probed with anti-CPL-1 pro-region antibody. The upper band shows the wild-type protein (approximately 36 kDa) and lower band shows the mutant CPL-1 protein (approximately 22 kDa).





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