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Fig. 6. Cytoplasmic vesicles induced by rab7 RNAi form before Caenorhabditis elegans cpl-1(ok360) mutant vesicles. (A,C) YP170::GFP accumulates in slightly enlarged cytoplasmic vesicles in rab7(RNAi) embryos (A) and rab7(RNAi)/cpl-1(ok360) double mutant embryos (C). The fluorescent vesicles are of similar size, but less abundant in the double mutant (C). (B,D) Immunofluorescence with YP170 antibody in rab7(RNAi) embryo (B) and cpl-1(ok360)/rab7(RNAi) double mutant embryo (D). Arrowheads indicate the abnormally large yolk vesicles that accumulate only in the double mutant.





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