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Fig. 1. RNAi of ubc-2 and apc-11 show indistinguishable embryonic phenotypes in Caenorhabditis elegans. Several embryos from each RNAi treatment are shown. The left panels show DAPI staining and the right panels show pHisH3 staining to detect metaphase figures. These embryos have all failed to complete the first cell division and the meiotic arrest phenotype is apparent in both sets of RNAi. Representative oocyte metaphase chromosomes are indicated with arrows and sperm chromatin is indicated by carets. During the meiotic divisions of the oocyte chromosomes, the quiescent, hypercondensed sperm chromatin mass does not stain with pHisH3 antibodies (Golden et al., 2000).





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