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Fig. 9. Fusion of GWBs. (A) A continuous sequence of live cell images showing the fusion of two GFP-labeled GWBs into one (arrows) in a HEp-2 cell transfected with a plasmid construct expressing a GFP-GW182 fusion protein. Original magnification x1,500. (See also movie 2 in supplementary material.) (B) ImmunoEM images of protein A-gold-labeled cytoplasmic structures that may be GWBs undergoing fusion (or division). Dotted lines encircle the potential GWBs undergoing fusion similar to the type observed in A.





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