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Fig. 8. Anti-ß1-integrin does not activate Bid, the release of cytochrome c and caspase-9 in c-FLIPL overexpressing keratinocytes. c-FLIPL HaCaT cells and mock infected cells were cultivated in the presence of anti-ß1-integrin or irrelevant IgG antibody. Proteins were extracted from the full cell lysate for caspase-8, caspase-9 and Bid (A), whereas they were extracted from mitochondria and cytosol for cytochrome c (B). Western blot was performed with anti-procaspase-9, anti-procaspase-8, anti-Bid and anti-cytochrome c antibodies. ß-actin was used to normalize protein content.





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