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Fig. 4. Staining with anti-laminin and anti-nidogen antibodies reveals that the BM of Hsp47–/– embryos at 10.5 dpc is fractured. (A-E) Neural tube regions of wild-type and Hsp47–/– embryos were analysed for the immunolocalization of laminin (A,B), nidogen-1 (C,D) and fibronectin (E,F). Arrows indicate BM regions. Bar, 50 µm.





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