spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 5. The sem1{Delta} rpn10{Delta} double mutant has severe defects in RP lid integrity and DNA damage resistance. (A) Synthetic lethal interactions between sem1{Delta} and rpn10{Delta} at 36°C. (B) Disruption of the lid and dissociation of the lid from the base in sem1{Delta} rpn10{Delta} cells. Superose 6 fractions were subjected to immunoblot analysis with antibodies to the indicated proteins. (C) CP activity of the same column fractions used in B. (D) Growth defects of mutants exposed to canavanine, UV irradiation or hydroxyurea (HU). Cells were spotted onto plates in fivefold serial dilutions and were subjected to the indicated treatments at 30°C.





Right arrow Return to article