(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.
Fig. 2. Specificity of the p38 and JNK inhibitors. (A) Cells were incubated with Fas-mAb for 1 hour in the absence (lane 2) or presence of PD169316 (lane 3), SP600125 (lane 4) or both (lane 5). Fas-induced increase in p38 activity was inhibited by PD169316 but not SP600125. (B) Phosphorylation of JUN by JNK was inhibited by SP600125 but was unaffected by PD169316. Inhibition of both kinases was observed only in cells treated with both inhibitors.
