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Fig. 1. Light micrographs of purified sheets of RPE cells from (A) shaker1 control (Myo7a+/4626SB) and (B) shaker1 mutant (Myo7a4626SB/4626SB) mouse retinas. Apical processes are evident as lightly stained region below the cell bodies (indicated by square brackets). In the control RPE, melanosomes are present in the apical processes, whereas the apical processes of the mutant RPE are devoid of melanosomes. Bar, 10 µm.





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