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Fig. 3. A model for the initiation and development of the FSM on the outer plaque of the SPB. (I) The nucleus contains a three-layered, unmodified SPB. Cytoplasmic vesicles, which carry components of LEPs, are observable. (II) These vesicles gather on the outer plaque of SPBs. Remarkably, the outer plaque develops to be a meiotic outer plaque (MOP), which contains several specific proteins. (III) A FSM precursor is formed by fusion of vesicles. t-SNAREs are recruited to the FSM precursor. A LEP complex is formed at the leading edge of the FSM. (IV) Cells enter anaphase II. The FSM grows by fusion with cytoplasmic vesicles that carry v-SNARE proteins. (V) The FSM engulfs the nucleus and a part of the cytoplasm. Closure of the FSM forms a membrane compartment called the prespore, which contains a haploid nucleus and part of the mother cell cytoplasm.





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