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Fig. 5. Expression of tenascin-W and tenascin-C in the adult mouse. Each figure shows double staining of tenascin-W (green) and tenascin-C (red), with the overlap being yellow. Tenascin-C immunoreactivity is found in the molecular layer (ml) of the cerebellum (A). Tenascin-W was not detected here or elsewhere in the adult central nervous system. Tenascin-W and tenascin-C co-localize in the matrix of kidney tubules (B). Tenascin-C is found in the matrix of major blood vessels but tenascin-W is expressed only at the base of the cusps (c) of the aortic (arrow, C) and pulmonary valves. Tenascin-W is also expressed as a subset of the tenascin-C expression pattern in the corneal limbus (lm, D) and the periosteum (po) of the rib (r) (E). Tenascin-C is seen in the matrix of adult stomach (F) and intestine (G), but tenascin-W is not. c, valve cusp; cb, ciliary body; co, cornea; g, glands; icm, intercostal muscle; me, muscularis externa; ml, molecular layer; mm, muscularis mucosa; Pcl, Purkinje cell layer; sm, submucosa; t, tendon; v, villus. Scale bar, 200 µm.





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