spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 7. The pH dependence of dextran trafficking. Osteoclasts were plated on dentine disks and incubated for 16 hours before a 30 minute pre-incubation with 25 nM bafilomycin A1 or vehicle control. TRITC-labelled dextran-3000 was then added for 5 minutes before fixation and immunodecoration with antibodies against the {alpha}vß3 integrin. Representative single CSLM sections for cells treated with the vehicle control (A) or bafilomycin A1 (B) are shown; the outline of the cells as delineated by {alpha}vß3 antibodies is depicted by a dashed white line. Scale bar, 10 µm. The number of osteoclasts presenting endocytosed dextran was counted and expressed as the percentage of endocytosis inhibition ± s.e.m. (Table).





Right arrow Return to article