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Fig. 7. Calpain inhibition results in apical relocalization of basal bodies in foxj1-/- trachea. (A,B) By transmission electron microscopy, basal bodies (arrowheads) are found to be apically localized in an E17.5 foxj1+/+ tracheal explant (A), but distributed throughout the cytoplasm of foxj1-/- tracheal explant (B); both cultured for 96 hours. (C) Treatment of cultured E17.5 foxj1-/- tracheal explant with 10 mM calpain II inhibitor results in localization of basal bodies (arrowheads) to cell apex. Scale bars: 500 nm (A,B); 250 nm (C).





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