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Fig. 7. The number of actin foci decreased in the posterior region during the retraction phase. Panels A-L and A'-L' show sequential images of actin foci in two representative migrating cells. The actin foci were marked with white spots. M and M' show the time course of the area gained by the cells shown in A-L and A'-L'. The cells alternated between the extension and the retraction phases. Note that the changes in the distribution of actin foci were correlated with the cyclic phase changes during migration. From the late extension phase to the early retraction phase, the number of actin foci in the posterior region decreased (C-E, I-J, C'-D' and I'-K'). Scale bar: 5 µm.