JCS01035 Supplemental Figures

Files in this Data Supplement:

• Figure S1 -

  Fig. S1. Partitioning of MMP9 chimeras into distinct membrane domains. Confocal microscopy of MMP9-expressing cells stained with cholera toxin b-subunit (green) and anti-MMP9 antibody (red); yellow staining indicates colocalization of the molecules. (n =50). Bar, 10 mm.

• Figure S2 -

  Fig. S2. Doxycycline does not affect the growth of mock xenografts. (A) Average tumor size at 17 weeks of xenografts implanted in untreated (-dox) and doxycycline-treated mice (+dox). (B) Tumor growth kinetics in mice represented in A over a 17-week period. Mean values ± s.e.m. are represented.