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Fig. 6. Imaging of osteocytes by transmission electron microscopy. (A-D) 48-day-old wild-type (A,B) and MT1-MMP-deficient (C,D) littermates. (A) Osteocyte (os) residing in lacuna (Lac). Notice the well-defined cell processes and canaliculi seen in cross section (arrows). (B) Section of osteocyte intersecting two well-defined processes (P). The matrix around the processes is electron dense and granular in appearance. (C,D) Osteocytes from MT1-MMP-deficient littermate displaying canaliculus (Can). Bar, 1 µm.





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