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Fig. 1. Schematic of human CAP350. The CAP350 cDNA is predicted to encode a protein of 3117 amino acids. The locations of the conserved CAP-Gly domain and of the two putative LxxLL nuclear hormone receptor-interacting signature motifs in CAP350 are indicated. KM3 indicates the extent of two independently isolated, partial HeLa cell cDNA clones obtained from yeast two-hybrid screens for PPAR{alpha}-interacting proteins (Miyata et al., 1996) and corresponds to amino acids 572-1176 of CAP350.





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