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Fig. 2. Genotype of the keratinocyte-specific HB-EGF-deficient mice. (A-C) Keratinocyte-specific HB-EGF-deficient mice were confirmed by PCR as lox homozygous (A), Cre-recombinase positive (B) and lox-out (C). (D) Keratinocyte-specific disruption of HB-EGF mRNA in HB–/– mice was confirmed by RT-PCR. KC, keratinocytes.





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