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Fig. 6. Involvement of Rho-effector proteins in the regulation of endosome transport downstream of RhoB. Cells expressing myc-RhoB^G14V showed peripheral RhoB^G14V-positive endosomes (a) and diffuse actin filaments (b) after 1h treatment with the ROCK inhibitor Y-27632. Co-expression of myc-RhoB^G14V and a GFP-tagged dominant negative Dia1-N1 Dia1 (Dia1-N1) blocked the dispersion of RhoB-positive vesicles (c). Dia1-N1 partially co-localised with RhoB (merge of c and d). Bars: 10 µm.

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