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Fig. 9. An active mutant of Dia1 mimics RhoB effects. Expression of GFP-mDia1-{Delta}N3 (Dia1-{Delta}N3) induces the dispersion of EEA1-positive endosomes and the formation of thin parallel actin fibres (a,b, asterisk marks injected cell). Dia1-{Delta}N3 is targeted to vesicles and induces the assembly of an actin coat around them (c,d and high magnification insets). Bars: 10 µm.





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