spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. uPAR mediates uPA-dependent upregulation of C5aR expression. The quiescent MCs were stimulated for 20 hours with 20 nM uPA in the presence or absence of 5 µg/ml anti-uPAR monoclonal antibody, and C5aR expression was investigated at the mRNA (A) and protein (B) levels using RT-PCR TaqMan analysis and western blotting, respectively. MCs incubated in medium without uPA and anti-uPAR antibody served as a control. The results in A are presented as mean ± s.e.m. for three separate and independent experiments. The data on the upper panel in B are representative of three separate and independent experiments. Quantification of the results of these experiments by densitometry presented as mean ± s.e.m. is shown in the lower panel. Significance between control unstimulated and stimulated cells was determined by Student's t-test (*P<0.05).





Right arrow Return to article