spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. TheTyk2/Stat3 pathway mediates uPA-induced upregulation of C5aR in MCs. Quiescent MCs that were uninfected or infected with wild-type Ad5Tyk2, the Tyk2 mutants, Ad5Tyk2{Delta}C and Ad5Tyk2KE, or with the Ad5STAT3F mutant form of Stat3 were stimulated with 20 nM uPA for 20 hours, and RT-PCR analysis for C5aR mRNA was performed using the TaqMan method. MCs incubated in medium without uPA served as a control. Results are presented as mean ± s.e.m. of three independent experiments.





Right arrow Return to article