spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 3. PtdOH and PtdIns(4,5)P2 regulate integrin-mediated adhesion. Following the maintenance of cells in suspension for 60 minutes to reduce PLD activity to basal levels, cells were treated with 10 mg ml–1 of function-blocking antibodies to either ß1 or ß2 integrins or vehicle (no antibody) and either 100 µM PtdOH, 100 µM PtdIns(4,5)P2 or vehicle (no lipid) before their adhesion was quantified to wells coated with (A) serum, (B) FN or (C) ICAM1. Using a Student's t-test, P values of <0.01% were obtained (*, ** and ***). Similar results were obtained in at least three separate experiments and error bars represent the standard deviation from the mean.





Right arrow Return to article