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Fig. 1. Drp1-mediated fission in MTP18-myc transfected cells. High magnification confocal microscopy images of mitochondria from MTP18-myc transfected COS-7 cells. Images show overview and close-up view of mitochondrial morphology (anti-MTP18, red) and Drp1 localisation (arrows, anti-Drp1, green) before (A) and after fragmentation (B). Double-arrows indicate mitochondrial constrictions at sites were Drp1 localises.





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