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Fig. 3. In the CD8-4C chimera, both YXXV and YXXGL motifs are functional. (A) Representative confocal images of CD8-4C chimeras with point mutations in the intracellular domain following live-labeling with anti-CD8 as described in Materials and Methods. Bars, 10 µm. (B) Histogram, showing the proportion of protein detected at the cell surface (red) or in internal compartments (green) after labeling (n=61-76). **, P<0.01.





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